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A huge effort has been invested in bone tissue engineering, in which a highly porous scaffold plays a critical role in guiding bone and vascular tissue growth and regeneration in three dimensions. Hence, the engineered tissue construct is an artificial scaffold populated with living cells and signalling molecules.

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growth factors) and extracellular matrix (ECM). Natural tissues consist of three components: cells, signalling systems (e.g. Tissue engineering is essentially a technique for imitating nature.

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